Center for Vaccine Research

Derek Trobaugh, PhD

  • Research Assistant Professor
  • Immunology

Representative Publications

  • Of Mice and Men: Protective and Pathogenic Immune Responses to West Nile virus Infection. Trobaugh D, Green S. Curr Trop Med Rep. 2015 Mar 1;2(1):41-48.
  • The 5' and 3' ends of alphavirus RNAs--Non-coding is not non-functional. Hyde JL, Chen R, Trobaugh DW, Diamond MS, Weaver SC, Klimstra WB, Wilusz J. Virus Res. 2015 Aug 3;206:99-107. doi: 10.1016/j.virusres.2015.01.016. Epub 2015 Jan 25.
  • Human trophoblasts confer resistance to viruses implicated in perinatal infection. Bayer A, Delorme-Axford E, Sleigher C, Frey TK, Trobaugh DW, Klimstra WB, Emert-Sedlak LA, Smithgall TE, Kinchington PR, Vadia S, Seveau S, Boyle JP, Coyne CB, Sadovsky Y. Am J Obstet Gynecol. 2015 Jan;212(1):71.e1-8. doi: 10.1016/j.ajog.2014.07.060. Epub 2014 Aug 6.
  • Can understanding the virulence mechanisms of RNA viruses lead us to a vaccine against eastern equine encephalitis virus and other alphaviruses? Trobaugh DW, Ryman KD, Klimstra WB. Expert Rev Vaccines. 2014 Dec;13(12):1423-5. doi: 10.1586/14760584.2014.944168. Epub 2014 Jul 30.
  • A viral RNA structural element alters host recognition of nonself RNA. Hyde JL, Gardner CL, Kimura T, White JP, Liu G, Trobaugh DW, Huang C, Tonelli M, Paessler S, Takeda K, Klimstra WB, Amarasinghe GK, Diamond MS. Science. 2014 Feb 14;343(6172):783-7. doi: 10.1126/science.1248465. Epub 2014 Jan 30.
  • RNA viruses can hijack vertebrate microRNAs to suppress innate immunity. Trobaugh DW, Gardner CL, Sun C, Haddow AD, Wang E, Chapnik E, Mildner A, Weaver SC, Ryman KD, Klimstra WB. Nature. 2014 Feb 13;506(7487):245-8. doi: 10.1038/nature12869. Epub 2013 Dec 18.
  • Altered effector functions of virus-specific and virus cross-reactive CD8+ T cells in mice immunized with related flaviviruses. Trobaugh DW, Yang L, Ennis FA, Green S. Eur J Immunol. 2010 May;40(5):1315-27. doi: 10.1002/eji.200839108.